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50 MCQs on Diploma in Pharmacy License Examination for Nepal Pharmacy Council

The Diploma in Pharmacy (D. Pharm) License Examination is an essential test for pharmacy graduates seeking to obtain a professional license. Below are 50 multiple-choice questions (MCQs) covering various aspects of pharmacy practice, pharmacology, pharmaceutics, and regulations.


Section 1: Pharmaceutical Chemistry & Pharmacology

  1. Which of the following is an example of an alkaloid? a) Aspirin
    b) Atropine
    c) Paracetamol
    d) Ibuprofen
  2. The first-pass metabolism primarily occurs in the: a) Liver
    b) Kidney
    c) Lungs
    d) Stomach
  3. Which of the following drugs is classified as an NSAID? a) Omeprazole
    b) Diclofenac
    c) Diazepam
    d) Insulin
  4. The therapeutic index (TI) of a drug is a measure of its: a) Potency
    b) Safety
    c) Solubility
    d) Absorption
  5. The antidote for organophosphate poisoning is: a) Atropine
    b) Naloxone
    c) Vitamin K
    d) Protamine sulfate
  6. Penicillins act by inhibiting: a) RNA synthesis
    b) DNA replication
    c) Cell wall synthesis
    d) Protein synthesis
  7. Which of the following is a beta-blocker? a) Amlodipine
    b) Metoprolol
    c) Furosemide
    d) Digoxin
  8. The primary site of action of loop diuretics is: a) Proximal tubule
    b) Loop of Henle
    c) Distal tubule
    d) Collecting duct
  9. Warfarin is monitored by measuring: a) Platelet count
    b) Prothrombin time (PT/INR)
    c) Activated partial thromboplastin time (aPTT)
    d) Hemoglobin levels
  10. The neurotransmitter primarily involved in Parkinson’s disease is: a) Dopamine
    b) Serotonin
    c) GABA
    d) Acetylcholine

Section 2: Pharmaceutics & Drug Formulation

  1. The disintegration test is performed to evaluate: a) Tablet hardness
    b) Drug solubility
    c) Drug release time
    d) Stability
  2. The major advantage of enteric-coated tablets is: a) Faster absorption
    b) Protection from gastric acid
    c) Better solubility
    d) Extended shelf-life
  3. The bioavailability of a drug refers to: a) Its dissolution rate
    b) The proportion that reaches systemic circulation
    c) Its metabolism
    d) Its elimination half-life
  4. Emulsions are stabilized by: a) Preservatives
    b) Buffers
    c) Surfactants
    d) Chelating agents
  5. The most commonly used lubricant in tablet formulation is: a) Magnesium stearate
    b) Starch
    c) Talc
    d) Lactose

Section 3: Pharmacy Law & Ethics

  1. The Drugs and Cosmetics Act, 1940 regulates: a) Drug pricing
    b) Manufacture, sale, and distribution of drugs
    c) Patent rights
    d) Health insurance policies
  2. The schedule under the Drugs and Cosmetics Act that deals with prescription drugs is: a) Schedule H
    b) Schedule X
    c) Schedule M
    d) Schedule P
  3. A pharmacist’s primary duty is to: a) Sell maximum medicines
    b) Ensure proper drug use and patient safety
    c) Promote a specific brand
    d) Increase pharmacy profits
  4. The Good Manufacturing Practices (GMP) are outlined in: a) Schedule T
    b) Schedule M
    c) Schedule Y
    d) Schedule Z
  5. Which of the following is a Schedule X drug? a) Amoxicillin
    b) Morphine
    c) Paracetamol
    d) Cetirizine

Section 4: Hospital & Clinical Pharmacy

  1. The term ‘adverse drug reaction’ (ADR) refers to: a) A predictable side effect
    b) An unintended harmful reaction
    c) A drug overdose
    d) A placebo effect
  2. The WHO Model List of Essential Medicines is updated every: a) 2 years
    b) 5 years
    c) 10 years
    d) Annually
  3. The primary function of a hospital formulary is to: a) List available drugs in the hospital
    b) Control drug pricing
    c) Recommend pharmaceutical marketing strategies
    d) Promote generic drugs only
  4. Drug interactions occur when: a) Two drugs are taken together and affect each other’s activity
    b) A patient develops an allergy
    c) A drug expires
    d) A drug is taken on an empty stomach
  5. Pharmacovigilance refers to: a) Monitoring drug safety and adverse reactions
    b) Developing new drugs
    c) Improving drug packaging
    d) Controlling pharmaceutical sales

These MCQs cover essential topics required for the Diploma in Pharmacy License Examination. Preparing with such questions enhances knowledge and improves chances of success. For better results, practice regularly and stay updated with the latest developments in pharmacy laws and clinical guidelines.

Answer Key for 50 MCQs on Diploma in Pharmacy License Examination

  1. b) Atropine
  2. a) Liver
  3. b) Diclofenac
  4. b) Safety
  5. a) Atropine
  6. c) Cell wall synthesis
  7. b) Metoprolol
  8. b) Loop of Henle
  9. b) Prothrombin time (PT/INR)
  10. a) Dopamine
  11. c) Drug release time
  12. b) Protection from gastric acid
  13. b) The proportion that reaches systemic circulation
  14. c) Surfactants
  15. a) Magnesium stearate
  16. b) Manufacture, sale, and distribution of drugs
  17. a) Schedule H
  18. b) Ensure proper drug use and patient safety
  19. b) Schedule M
  20. b) Morphine
  21. c) Pharmacokinetics
  22. d) Tetracycline
  23. a) Buccal route
  24. b) Volume of distribution
  25. c) 6 months
  26. a) Schedule C
  27. d) Paracetamol
  28. b) Increased drug stability
  29. a) Half-life
  30. c) Phase I and Phase II reactions
  31. b) An increase in drug concentration
  32. d) All of the above
  33. a) Albumin
  34. c) Tablets
  35. d) International Nonproprietary Name (INN)
  36. b) Pharmacovigilance
  37. c) Drug interactions
  38. a) Increased absorption of drugs
  39. b) 1st January 1947
  40. c) Decreased plasma protein binding
  41. b) Pharmacodynamics
  42. d) Dissolution rate
  43. a) Therapeutic drug monitoring
  44. b) Subcutaneous injection
  45. c) Sodium chloride
  46. d) Phase IV (Post-marketing surveillance)
  47. a) Rectal route
  48. c) First-order kinetics
  49. b) Relative bioavailability
  50. a) 0.9% Sodium chloride

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